Prussia/South Italy

Prussia/South Italy is an uncommon pairing involving the characters Prussia and Romano. It is sometimes referred to as Prumano (from Prussia and Romano).

Interactions
In World Stars, 281 to 284, Prussia realizes that Romano gets a little stunned and excited about stories of his knighthood.

In another strip, Prussia observes Romano working, surprised how he is a hard worker. He asks if Romano doesn't have the money to buy shoes, and Romano replies that it's just that he prefers to use his money for more important things. Besides, Romano seems to feel comfortable enough to sleep in the presence of Prussia.

In a strip called "The one that wasn't there", Romano is depressed that he didn't get the main character in the movie and people always prefer his young brother. Then, Prussia shows up and extend a helping hand to him, saying that they should make their own movie "A movie that we truly want ...!".

In addition, Himaruya likes to relate the characters in illustrations where Prussia seems to want to provoke Romano, both calling him "Ita-chan's older brother" and commenting about him being the smallest of the four.

In a blog entry, Himaruya stated that Prussia holds the same feelings for Romano as he does for Veneziano, and he is attracted to their climate and topography.

Fan Speculations
Both Prussia and Romano have younger siblings, and are often overlooked in favor of their brothers. Even though they are complete opposites, they are said to be able to understand each other.